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The circadian clock: Understanding nature's timepiece

New light on a complex mechanismA cluster of brain cells less than half the size of a pencil eraser tells you when to wake up, when to be hungry and when it's time to go to sleep. The same cells also cause you to be disoriented after you've flown across multiple time zones.The human circadian clock, comprised of about 20,000 time-keeping cells, has mystified scientists since it was pinpointed in the brain about 30 years ago. Now, a researcher at the University of Calgary is getting a little bit closer to understanding how it ticks.