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Throwing the micro switch: MicroRNA may link smoking risk gene to neurobiology of addiction During the past several years, significant progress has been made in identifying susceptibility genes for nicotine dependence through genetic linkage and association analyses. Although a large number of genes have been associated with tobacco smoking, only a very limited number of genetic variants are considered to be causative. How to find these functional variants and then characterize them remains challenging in the field of human genetics.
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