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Active mechanism locks in the size of a cell's nucleus

Cells know that size matters, especially when it comes to the nucleus. In the early 1900s, German scientists first proposed that the size of a nucleus is always proportional to the size of its cell. Now, more than a century later, researchers at Rockefeller University show that an active mechanism controls this process. This mechanism, however, doesn`t reside within the nucleus as many once thought, but instead comes from the cell`s cytoplasm.