News

Crystal structure enables tailoring of pharmaceuticals against asthma

Researchers at Karolinska Institutet in Sweden have managed to elucidate the crystal structure of a human membrane protein - LTC4 synthase - which has a major influence on the development of asthma. LTC4 synthase is extremely difficult to analyze, and previously only low resolution information has been available on two membrane protein structures from human. The scientists now believe that their work will enable the development of new and better therapeutics against inflammations in the pulmonary tract.