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Microscopes reach new depths Physicists in China have made a new type of atomic force microscope (AFM) that works in liquid. The device could be used to image biological samples, materials that are easily oxidized and samples in hazardous environments (D Zhang et al. 2005 Rev. Sci. Instrum. 76 053705). Most AFMs work in air or in ultrahigh vacuum but in some cases the sample needs to be kept in a liquid, such as biological samples that can die in air.
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